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Original Article 


A Prospective study of BISAP score in Acute Pancreatitis.

Raga Veena P, Rup Kumar K.

Abstract
Background: Acute pancreatitis is defined as an inflammatory process of the pancreas with possible peri pancreatic tissue and multi-organ involvement inducing Multi-Organ Dysfunction Syndrome (MODS) with an increased mortality rate.The underlying mechanism of injury in pancreatitis is thought to be premature activation of pancreatic enzymes within the pancreas, leading to a process of auto digestion. Due to the risk of rapid deterioration in severe acute pancreatitis, the assessment of severity becomes crucial to a clinician. Multiple risk stratification tools for acute pancreatitis have been developed, but their clinical usefulness is limited. In Ranson's criteria and modified Glasgow score there are multiple parameters, of which some of them are not available in majority of hospitals in India. In addition, both are assessed after 48hrs, thereby missing potentially valuable early therapeutic window. The APACHE II score (Acute Physiology and Chronic Health Evaluation) is the most widely used prediction system currently, but it requires the collection of large number of parameters some of which may not be relevant to prognosis. APACHE II was originally developed as an intensive care instrument. For this purpose, a simple and accurate clinical scoring system that is, Bedside Index for Severity in Acute Pancreatitis (BISAP) scoring system was developed. This scoring system is used for stratifying patients according to their risk of mortality and is able to identify patientsat increased risk of mortality prior to the onset of organ failure. More over the data for BISAP score is collected within the first 24hrs of hospitalization. The ability tostratify

patients early in their course is a major step in improving future management strategies in acute pancreatitis.

Methods:
A prospective study was done in cases of acute pancreatitis with the effectiveness of Bedside Index for Severity in Acute Pancreatitis (BISAP) scoring system is used for stratifying patients according to their risk of mortality and is able to identify patients at increased risk of mortality prior to the onset of organ failure

Results:
A total of 50 cases were taken and the Bedside Index for Severity in Acute Pancreatitis (BISAP) scoring system was calculated in assessing mortality and intermediate markers of severity in acute pancreatitis in 24 hours of presentation. It is observed that individuals with BISAP score ‚Č•3 were 4.5 times more likely to develop organ failure and 6 times more likely to develop pancreatic necrosis, than those with BISAP score <3. Thus, confirming the efficacy of the BISAP score in predicting the mortality and morbidity associated with acute pancreatitis.

Conclusion:

The BISAP score is a simple and accurate method for the early identification of acute pancreatitis at increased risk for in hospital mortality.
BISAP score is efficient in identification of patients of acute pancreatitis who are at the risk of developing intermediate markers of severe pancreatitis in the first 24hours of presentation.

Key words: Acute pancreatitis; Ransonís score; Glasgow score; BISAP


 
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Pubmed Style

P RV, K RK. A Prospective study of BISAP score in Acute Pancreatitis.. doi:10.5455/nmj/00000187


Web Style

P RV, K RK. A Prospective study of BISAP score in Acute Pancreatitis.. http://www.narayanamedicaljournal.com/?mno=21249 [Access: December 24, 2020]. doi:10.5455/nmj/00000187


AMA (American Medical Association) Style

P RV, K RK. A Prospective study of BISAP score in Acute Pancreatitis.. doi:10.5455/nmj/00000187



Vancouver/ICMJE Style

P RV, K RK. A Prospective study of BISAP score in Acute Pancreatitis.. doi:10.5455/nmj/00000187



Harvard Style

P, R. V. & K, . R. K. (2020) A Prospective study of BISAP score in Acute Pancreatitis.. doi:10.5455/nmj/00000187



Turabian Style

P, Raga Veena, and Rup Kumar K. 2020. A Prospective study of BISAP score in Acute Pancreatitis.. doi:10.5455/nmj/00000187



Chicago Style

P, Raga Veena, and Rup Kumar K. "A Prospective study of BISAP score in Acute Pancreatitis.." doi:10.5455/nmj/00000187



MLA (The Modern Language Association) Style

P, Raga Veena, and Rup Kumar K. "A Prospective study of BISAP score in Acute Pancreatitis.." doi:10.5455/nmj/00000187



APA (American Psychological Association) Style

P, R. V. & K, . R. K. (2020) A Prospective study of BISAP score in Acute Pancreatitis.. doi:10.5455/nmj/00000187








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